| Extension | File Description |
| .SAS7SVEW | Uncommon Files |
| .SAT | CAD Files |
| .SATELLITE | Uncommon Files |
| .SATURN | Uncommon Files |
| .SAU | Uncommon Files |
| .SAUCE | Uncommon Files |
| .SAUCER | Uncommon Files |
| .SAUT | Uncommon Files |
| .SAV | Backup Files |
| .SAVAGE | Uncommon Files |
| .SAVE | Text Files |
| .SAVEDGAME | Uncommon Files |
| .SAVEDSEARC | System Files |
| .SAVER | System Files |
| .SAVGAO | Uncommon Files |
| .SAVINGS | Uncommon Files |
| .SAW | Uncommon Files |
| .SAX | Uncommon Files |
| .SAY | Uncommon Files |
| .SAZ | Uncommon Files |
| .SB | Audio Files |
| .SB0 | Uncommon Files |
| .SB1 | Uncommon Files |
| .SB2 | Uncommon Files |
| .SB3 | Uncommon Files |
| .SB4 | Uncommon Files |
| .SB5 | Uncommon Files |
| .SB6 | Uncommon Files |
| .SB7 | Uncommon Files |
| .SB8 | Uncommon Files |
| .SB9 | Uncommon Files |
| .SBA | Uncommon Files |
| .SBAK | Uncommon Files |
| .SBB | Backup Files |
| .SBC | Misc Files |
| .SBD | Data Files |
| .SBE | Uncommon Files |
| .SBF | Database Files |
| .SBG | Uncommon Files |
| .SBGF | Uncommon Files |
| .SBH | Uncommon Files |
| .SBI | Audio Files |
| .SBJ | Uncommon Files |
| .SBK | Video Files |
| .SBL | Uncommon Files |
| .SBM | Uncommon Files |
| .SBML | Developer Files |
| .SBN | System Files |
| .SBO | Uncommon Files |
| .SBP | CAD Files |
| .SBPF | Uncommon Files |
| .SBQ | Uncommon Files |
| .SBQ?? | Uncommon Files |
| .SBR | Developer Files |
| .SBS | Executable Files |
| .SBSONG | Uncommon Files |
| .SBT | Video Files |
| .SBTF | Uncommon Files |
| .SBU | Uncommon Files |
| .SBV | Uncommon Files |
| .SBW | Data Files |
| .SBX | Compressed Files |
| .SBY | Uncommon Files |
| .SBZ | Uncommon Files |
| .SB_ | Uncommon Files |
| .SC | Developer Files |
| .SC$ | Uncommon Files |
| .SC0 | Uncommon Files |
| .SC1 | Uncommon Files |
| .SC2 | Audio Files |
| .SC3 | Game Files |
| .SC4 | Game Files |
| .SC4DESC | Game Files |
| .SC4LOT | Game Files |
| .SC4MODEL | 3D Image Files |
| Extension | File Description |
| .SC4PATH | Uncommon Files |
| .SC5 | Uncommon Files |
| .SC6 | Game Files |
| .SC68 | Uncommon Files |
| .SC7 | Uncommon Files |
| .SC8 | Uncommon Files |
| .SC9 | Uncommon Files |
| .SC? | Audio Files |
| .SCA | Data Files |
| .SCALA | Uncommon Files |
| .SCAN | Uncommon Files |
| .SCANNER | Uncommon Files |
| .SCAR | Executable Files |
| .SCARS | Uncommon Files |
| .SCB | Executable Files |
| .SCC | Text Files |
| .SCD | Data Files |
| .SCE | Uncommon Files |
| .SCE2 | Uncommon Files |
| .SCENARIO | Uncommon Files |
| .SCENE | Game Files |
| .SCF | Data Files |
| .SCG | Raster Image Files |
| .SCH | Settings Files |
| .SCHDOC | Uncommon Files |
| .SCHED | Uncommon Files |
| .SCHEDULER | Uncommon Files |
| .SCHEMAS | System Files |
| .SCI | Raster Image Files |
| .SCJ | Uncommon Files |
| .SCK | Uncommon Files |
| .SCL | Uncommon Files |
| .SCM | Plugin Files |
| .SCN | Data Files |
| .SCO | Disk Image Files |
| .SCODL | Uncommon Files |
| .SCORE | Uncommon Files |
| .SCOREFONT | Uncommon Files |
| .SCORERS | Uncommon Files |
| .SCORES | Uncommon Files |
| .SCOTT | Uncommon Files |
| .SCP | Raster Image Files |
| .SCPR | Uncommon Files |
| .SCPT | Executable Files |
| .SCQ | Uncommon Files |
| .SCQ?? | Uncommon Files |
| .SCR | Executable Files |
| .SCR1 | Uncommon Files |
| .SCR2 | Uncommon Files |
| .SCRAP | Uncommon Files |
| .SCREEM | Uncommon Files |
| .SCREEN | Uncommon Files |
| .SCRIPT | Executable Files |
| .SCRIPTLAS | Uncommon Files |
| .SCRN | Uncommon Files |
| .SCROLL | Uncommon Files |
| .SCROLL2 | Uncommon Files |
| .SCROLL7 | Uncommon Files |
| .SCS | Game Files |
| .SCSF | Uncommon Files |
| .SCSI | Uncommon Files |
| .SCSPACK | Uncommon Files |
| .SCSV | Uncommon Files |
| .SCS_TOR | Uncommon Files |
| .SCT | Raster Image Files |
| .SCT?? | Uncommon Files |
| .SCU | Raster Image Files |
| .SCURL | Text Files |
| .SCV | Vector Image Files |
| .SCW | Misc Files |
| .SCX | Database Files |
| .SCY | Uncommon Files |
| .SCZ | Data Files |
| .SD | Audio Files |
| .SD! | Uncommon Files |
